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Hajime Sasaki Selected Research

isomaltulose (palatinose)

9/2015Effect of nutritional counseling and long term isomaltulose based liquid formula (MHN-01) intake on metabolic syndrome.
8/2011A new immune-modulating diet enriched with whey-hydrolyzed peptide, fermented milk, and isomaltulose attenuates gut ischemia-reperfusion injury in mice.
9/2009Improvement of glucose metabolism in patients with impaired glucose tolerance or diabetes by long-term administration of a palatinose-based liquid formula as a part of breakfast.
8/2007Dietary palatinose and oleic acid ameliorate disorders of glucose and lipid metabolism in Zucker fatty rats.
6/2007A palatinose-based balanced formula improves glucose tolerance, serum free fatty acid levels and body fat composition.
5/2007The Anti-Obesity Effect of the Palatinose-Based Formula Inslow is Likely due to an Increase in the Hepatic PPAR-alpha and Adipocyte PPAR-gamma Gene Expressions.
4/2007Effects of a novel palatinose based enteral formula (MHN-01) carbohydrate-adjusted fluid diet in improving the metabolism of carbohydrates and lipids in patients with esophageal cancer complicated by diabetes mellitus.
8/2004Effect of a novel palatinose-based liquid balanced formula (MHN-01) on glucose and lipid metabolism in male Sprague-Dawley rats after short- and long-term ingestion.

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Hajime Sasaki Research Topics

Disease

12Inflammation (Inflammations)
11/2020 - 08/2008
11Infections
01/2022 - 01/2004
5Type 2 Diabetes Mellitus (MODY)
01/2016 - 04/2007
4Hepatitis
04/2012 - 05/2006
3Atrophy
01/2020 - 05/2012
3Bone Resorption
01/2019 - 01/2004
3Periodontitis
01/2019 - 05/2008
3Body Weight (Weight, Body)
11/2012 - 08/2008
3Obesity
07/2011 - 05/2007
3Hyperglycemia
08/2007 - 08/2004
2Vesico-Ureteral Reflux (Vesicoureteral Reflux)
01/2022 - 01/2017
2Multiple Myeloma
01/2021 - 01/2019
2Fibrosis (Cirrhosis)
01/2020 - 05/2006
2Neoplasms (Cancer)
01/2019 - 12/2015
2Periapical Periodontitis (Apical Periodontitis)
01/2018 - 01/2016
2Hypertension (High Blood Pressure)
10/2016 - 01/2016
2Non-alcoholic Fatty Liver Disease
01/2016 - 12/2014
2Glucose Intolerance
09/2015 - 09/2009
2Metabolic Syndrome (Dysmetabolic Syndrome X)
09/2015 - 06/2007
2Reperfusion Injury
12/2014 - 08/2011
2Hyperlipidemias (Hyperlipidemia)
11/2013 - 08/2007
2Carcinoma (Carcinomatosis)
05/2011 - 04/2007
2Alveolar Bone Loss
05/2008 - 12/2004
1Autoimmune Hepatitis
12/2021
1Autoimmune Pancreatitis
12/2021
1Cytokine Release Syndrome
01/2021
1Psoriasis (Pustulosis Palmaris et Plantaris)
11/2020
1Pruritus (Itching)
11/2020
1Prostatic Neoplasms (Prostate Cancer)
01/2020
1Osteomyelitis
02/2019
1Delayed Graft Function
12/2018
1Chronic Hepatitis B
10/2018
1Hepatocellular Carcinoma (Hepatoma)
10/2018
1Hypoxia (Hypoxemia)
01/2018
1Rheumatoid Arthritis
11/2016
1Osteonecrosis (Kienbock's Disease)
11/2016
1Multiple Sclerosis
11/2016
1Cytomegalovirus Infections (Inclusion Disease)
07/2016
1Alcoholic Fatty Liver
01/2016
1Coinfection
01/2016

Drug/Important Bio-Agent (IBA)

10CytokinesIBA
01/2019 - 01/2004
8isomaltulose (palatinose)IBA
09/2015 - 08/2004
7Glucose (Dextrose)FDA LinkGeneric
01/2016 - 08/2004
5Peptides (Polypeptides)IBA
12/2014 - 07/2011
3Interleukin-10 (Interleukin 10)IBA
02/2019 - 12/2004
3LipidsIBA
05/2017 - 04/2007
3L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
11/2014 - 05/2006
3CarbohydratesIBA
08/2007 - 08/2004
2Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 07/2012
2Immunoglobulins (Immunoglobulin)IBA
12/2021 - 01/2010
2Biological ProductsIBA
01/2021 - 01/2019
2Proteins (Proteins, Gene)FDA Link
01/2020 - 05/2008
2Sucrose (Saccharose)IBA
01/2016 - 08/2007
2Fluorouracil (Carac)FDA LinkGeneric
12/2015 - 02/2015
2Insulin (Novolin)FDA Link
09/2015 - 08/2008
2DextrinsIBA
09/2015 - 09/2009
2Biomarkers (Surrogate Marker)IBA
09/2015 - 11/2012
2Interleukin-6 (Interleukin 6)IBA
11/2012 - 07/2011
2Concanavalin AIBA
04/2012 - 08/2011
2Whey ProteinsIBA
04/2012 - 05/2006
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
07/2011 - 05/2006
2Interleukin-12 (IL 12)IBA
05/2008 - 01/2004
2Interleukin-1 (Interleukin 1)IBA
12/2004 - 01/2004
1HydrogelsIBA
01/2022
1gelatin methacryloylIBA
01/2022
1InterferonsIBA
01/2021
1Histones (Histone)IBA
01/2021
1calcipotriene (calcipotriol)FDA LinkGeneric
11/2020
1Prostaglandins AIBA
11/2020
1betamethasone-17,21-dipropionate (betamethasone dipropionate)FDA LinkGeneric
11/2020
1Azithromycin (Zithromax)FDA LinkGeneric
11/2020
1Calcineurin InhibitorsIBA
01/2020
1Hypoxia-Inducible Factor 1IBA
02/2019
1ArginaseIBA
02/2019
1Toll-Like Receptor 2IBA
02/2019
1UbiquitinsIBA
01/2019
1ChemokinesIBA
01/2019
1Macrophage Migration-Inhibitory FactorsIBA
01/2019
1Messenger RNA (mRNA)IBA
01/2019
1CXCR4 Receptors (CXCR4 Receptor)IBA
01/2019
1MicroRNAs (MicroRNA)IBA
10/2018
1Oxygen (Dioxygen)IBA
01/2018
1dihydroceramideIBA
05/2017
1Virulence Factors (Pathogenicity Factors)IBA
05/2017
1CD100 antigenIBA
11/2016
1Ganciclovir (Cytovene)FDA LinkGeneric
07/2016
1FoscarnetFDA LinkGeneric
07/2016
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
01/2016
1Toll-Like Receptors (Toll-Like Receptor)IBA
01/2016
1NF-kappa B (NF-kB)IBA
01/2016
1Linoleic Acid (Linoleate)IBA
01/2016

Therapy/Procedure

5Therapeutics
01/2021 - 11/2012
3Kidney Transplantation
01/2022 - 05/2012
2Transplantation
01/2017 - 05/2012
2Drug Therapy (Chemotherapy)
12/2015 - 02/2015
1Injections
01/2022
1Immunomodulation
11/2020
1Prostatectomy (Retropubic Prostatectomy)
01/2020
1Warm Ischemia
12/2018
1Organ Transplantation
07/2016